Polynucleotides

Polynucleotides are purified DNA fragments used in certain injectable skin-quality treatments. They are intended to support biological processes associated with tissue repair. They do not replace lost facial volume in the way a dermal filler can.

Many aesthetic polynucleotide products contain purified DNA fragments sourced from fish, commonly salmon or trout. Ingredients and manufacturing processes differ between brands. Please tell us about any fish allergies or other allergies before treatment so the specific product can be checked.

Product options may include Plinest, Plinest Eye and Newest, subject to availability and individual suitability. Plinest Eye is formulated for the area around the eyes; Newest combines polynucleotides with hyaluronic acid. We will confirm the exact product and its intended use at your consultation.

Certain products may be considered for the delicate under-eye area, particularly where fine lines or crepey texture are a concern. Dark circles can have many causes, including pigmentation, shadows and hollowing, so polynucleotides will not be the right answer for everyone.

A course of around two to four sessions, often spaced three to four weeks apart, may be recommended. The precise number and interval depend on the specific product, treatment area and individual response. Maintenance may be discussed after review.

Changes are usually gradual, with some people noticing improvements over the following weeks and further changes developing over several months. Results, their duration and the need for maintenance vary. We cannot promise a particular outcome.

Redness, small raised injection marks, swelling, tenderness or bruising are possible. These often settle over the following days, although recovery varies. We will give you aftercare instructions for the product and area treated.

All injectable treatments carry risks. Common reactions include swelling, bruising and discomfort; less common complications may include infection, allergic reactions or persistent lumps. A full consultation, informed consent and appropriate product selection are essential. Treatment may not be suitable for everyone.

Suitability depends on your medical history, allergies, medicines, pregnancy or breastfeeding status, active skin infections and the product’s instructions. We will review these factors before offering treatment and may recommend delaying or avoiding it.

Avoid touching or massaging injection sites unless specifically advised. Follow the tailored instructions provided at your appointment about skincare, make-up, exercise, heat and when to seek help. Contact the clinic if symptoms worsen or you are concerned after treatment.